Although US is predicted to clean up this year, its 50-year dominance will end, say analysts
           British DNA pioneer Professor Sir Alec Jeffreys has been tipped for an award.  Photograph: David Sillitoe for the Guardian
      American scientists will again sweep the majority of Nobel prizes  at this week's award announcements in Sweden, analysts have predicted.  But they have also warned this dominance may soon come to end.
David  Pendlebury, a citation analyst who has correctly predicted 10 Nobel  winners since 2002, believes that the countries of the east,  particularly China, will soon start to rule the awards for science's  greatest prize.
"In the first half of the 20th century the UK,  Germany, and France dominated the sciences. The US emerged as the world  leader after the second world war. Now, I believe we will begin to see  as many Nobel prize winners from Asia as we do from the US and Europe."  Pendlebury, who works for Thomson Reuters, was speaking on the eve of  the announcement of this year's awards. The prize for medicine will be  revealed tomorrow; physics on Tuesday and chemistry on Wednesday. The  peace prize will be announced on Thursday; economics next Monday; and  literature later this month. A maximum of three individuals will be  allowed to share a Nobel, with each prize being worth around £1m.
Over  the past 10 years, 31 out of the 76 individuals who won science Nobels  were American-based while 16 out of the 21 economics winners were from  the US. By contrast, Britain – a nation with a fair Nobel reputation –  won eight physiology prizes, one for physics and one for economics.  These overall figures are open to wide interpretation, however. Many  winners hold joint nationalities and are often claimed by both their  country of origin and their country of affiliation.
Nevertheless,  the figures do give a general indication of the gulf that separates the  US from the rest of the world, one that is likely to continue this year  according to Pendlebury. He has tipped a number of US teams as possible  winners including Robert Langer and Joseph Vacanti, both based in  Boston, for their work on tissue engineering; Sajeev John (Toronto,  Canada) and Eli Yablonovitch (Berkeley, California) for work on  photonics; and Allen Bard (Austin, Texas) for his work on scanning  electrochemical microscopy.
Pendlebury cautioned care about  betting on his predictions, however. "If you only consider the top 0.1%  of the most cited scientists in the world, that includes more than 1,000  researchers," added Pendlebury. "You can narrow it down but it gets  harder and harder to differentiate their contributions. In the end, it  rests with the individual preferences of Nobel committee members. Nobels  are currently dominated by US scientists. However, US investment in the  physical sciences is no longer as robust as its investment in  biological and medical sciences, so I think in the next decade or so we  will begin to see many more Nobel Prize winners from Asia."
As to  his own hopes for this week's prizes, Pendlebury admitted to a couple of  favourites. One is Sir Alec Jeffreys, the Leicester University  biochemist who, in 1984, developed the techniques of DNA fingerprinting  and profiling that have transformed forensic science. "Nobels are  usually given for theoretical work. However, prizes have been given for  applied work, such as fibre optics, and I would really like to see  Jeffreys rewarded for a discovery that has had an enormous impact on  society."
Pendlebury also champions the cause of Jacques Miller,  the 80-year-old French-Australian researcher who revealed the key role  of the thymus in controlling the body's immune system, a discovery of  immense medical importance. "It was a critical discovery, though Miller  made it 50 years ago. He is still doing research and it would be great  if he could get a Nobel.
"Of course, half a century may seem a  long time to wait for proper recognition for your work but it would not  be a record. The American researcher Peyton Rous had to wait until 1966  to be given a Nobel for his work that led to the discovery of  tumour-causing viruses, even though he carried it out in 1911. So I'm   still holding out hope for Jacques later this week."
Additional research by Phoebe Cooke
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